In abnormal creatinine clearance, which other parameter is affected besides creatinine?

In abnormal creatinine clearance, which other parameter is affected besides creatinine?

• A. BUN
• B. Calcium
• C. AST
• D. Glucose

Answer: (A)

Abnormal creatinine clearance signals reduced glomerular filtration, so the waste products the kidney normally removes also tend to accumulate. Blood urea nitrogen (BUN) is another waste product cleared by the kidneys, and its level typically rises when clearance decreases. That makes BUN commonly affected alongside creatinine in kidney dysfunction. The other options aren’t directly tied to filtration in the same way: calcium is regulated by calcium-phosphate balance and hormones, AST is a liver enzyme, and glucose is governed by metabolic control. So the parameter that changes with abnormal creatinine clearance is BUN.

Abnormal creatinine clearance signals reduced glomerular filtration, so the waste products the kidney normally removes also tend to accumulate. Blood urea nitrogen (BUN) is another waste product cleared by the kidneys, and its level typically rises when clearance decreases. That makes BUN commonly affected alongside creatinine in kidney dysfunction. The other options aren’t directly tied to filtration in the same way: calcium is regulated by calcium-phosphate balance and hormones, AST is a liver enzyme, and glucose is governed by metabolic control. So the parameter that changes with abnormal creatinine clearance is BUN.